map quest will only let me see 64-81....
From my house the stats are:
Total Est. Time: 4 hours, 58 minutes Total Est. Distance: 294.08 miles
1: Start out going SOUTH on INDIAN PLANTATION RD toward VA-603/INDIAN RIVER RD. <0.1 miles
2: Turn RIGHT onto VA-603/INDIAN RIVER RD. Continue to follow INDIAN RIVER RD. 5.3 miles
3: Turn LEFT onto ELBOW RD. 0.1 miles
4: Turn SLIGHT RIGHT onto INDIAN RIVER RD. 2.4 miles
5: Turn LEFT to stay on INDIAN RIVER RD. 1.9 miles
6: Merge onto I-64 W toward HAMPTON. 85.3 miles
7: Merge onto I-295 N via EXIT 200 toward WASHINGTON. 24.4 miles
8: Merge onto I-64 W via EXIT 53A toward CHARLOTTESVILLE. 90.1 miles
9: Merge onto I-81 S via the exit on the LEFT toward LEXINGTON/ROANOKE. 82.2 miles
10: Merge onto VA-311 S/THOMPSON MEMORIAL DR via EXIT 140 toward SALEM. 1.6 miles
11: Turn RIGHT onto US-460/E MAIN ST.
Total Est. Time: 4 hours, 58 minutes Total Est. Distance: 294.08 miles

From petersburg/460 the stats are (assumin ya take 95 to 64 to 81) are:

Total Est. Time: 3 hours, 32 minutes Total Est. Distance: 211.01 miles

mapquest sucks it and will not follow 460 to save its life