We had an 03 s55 AMG, and within the year we had it:
The supercharger blew
The rear right strut blew
The tranny computer fried
The trunk broke
The brakes had to be replaced twice
And random check engine lights all the time

The car was in the shop every two weeks, which is why we got rid of it. Maybe it was just that one, but Ive heard of very similar things happening to other MB. Just my .02c